Activity

Directional sound sensing plays a critical role in many applications involving the localization of a sound source. However, the sensing range limit and fabrication difficulties of current acoustic sensing technologies pose challenges in realizing compact subwavelength direction sensors. Here, a subwavelength directional sensor is demonstrated, which can detect the angle of an incident wave in a full angle range (0°∼360°). The directional sensing is realized with acoustic coupling of Helmholtz resonators each supporting a monopolar resonance, which are monitored by conventional microphones. When these resonators scatter sound into free-space acoustic modes, the scattered waves from each resonator interfere, resulting in a Fano-like resonance where the spectral responses of the constituent resonators are drastically different from each other. This work provides a critical understanding of resonant coupling as well as a viable solution for directional sensing. © 2020 Toyota Motor North America. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.Natural materials are often compositionally and structurally heterogeneous for realizing particular functions. Inspired by nature, researchers have designed hybrid materials that possess properties beyond each of the components. Particularly, it remains a great challenge to realize site-specific anisotropy, which widely exists in natural materials and is responsible for unique mechanical properties as well as physiological behaviors. Herein, the spontaneous formation of aligned graphene oxide (GO) flakes in sodium alginate (SA) matrix with locally controlled orientation via a direct-ink-writing printing process is reported. The GO flakes are spontaneously aligned in the SA matrix by shear force when being extruded and then arranged horizontally after drying on the substrate, forming a brick-and-mortar structure that could anisotropically contract or expand upon activation by heat, light, or water. By designing the printing pathways directed by finite element analysis, the orientation of GO flakes in the composite is locally controlled, which could further guide the composite to transform into versatile architectures. Particularly, the transformation is reversible when water vapor is applied as one of the stimuli. As a proof of concept, complex morphing architectures are experimentally demonstrated, which are in good consistency with the simulation results. © 2020 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.Loss of memory during Alzheimer’s disease (AD), a fatal neurodegenerative disorder, is associated with neuronal loss and the aggregation of amyloid proteins into neurotoxic β-sheet enriched structures. However, the mechanism of amyloid protein aggregation is still not well understood due to many challenges when studying the endogenous amyloid structures in neurons or in brain tissue. Available methods either require chemical processing of the sample or may affect the amyloid protein structure itself. Therefore, new approaches, which allow studying molecular structures directly in neurons, are urgently needed. A novel approach is tested, based on label-free optical photothermal infrared super-resolution microspectroscopy, to study AD-related amyloid protein aggregation directly in the neuron at sub-micrometer resolution. Using this approach, amyloid protein aggregates are detected at the subcellular level, along the neurites and strikingly, in dendritic spines, which has not been possible until now. Here, a polymorphic nature of amyloid structures that exist in AD transgenic neurons is reported. Based on the findings of this work, it is suggested that structural polymorphism of amyloid proteins that occur already in neurons may trigger different mechanisms of AD progression. © 2020 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.Sodium-ion energy storage is of the most attractive candidate for commercialization adoption due to the safety and cost demands of large-scale energy storage systems, but its low energy density, slow charging capability, and poor cycle stability are yet to be overcome. Here, a strategy is reported to realize high-performance sodium-ion energy storage using battery-type anode and capacitor-type cathode materials. First, nitrogen-doped mesoporous titanium dioxide (NMTiO2) structures are synthesized via the controlled pyrolysis of metal-organic frameworks. They exhibit interconnected open mesopores allowing fast ion transport and robust cycle stability with nearly 100% coulombic efficiency, along with rich redox-reactive sites allowing high capacity even at a high rate of ≈90 C. Moreover, assembling the NMTiO2 anode with the nitrogen-doped graphene (NG) cathode in an asymmetric full cell shows a high energy density exceeding its counterpart symmetric cell by more than threefold as well as robust cycle stability over 10 000 cycles. Additionally, it gives a high-power density close to 26 000 W kg-1 outperforming that of a conventional sodium-ion battery by several hundred fold, so that full cells can be charged within a few tens of seconds by the flexible photovoltaic charging and universal serial bus charging modules. © 2020 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.Lead-free halide double perovskites (HDPs) are promising candidates for high-performance solar cells because of their environmentally-friendly property and chemical stability in air. The power conversion efficiency of HDPs-based solar cells needs to be further improved before their commercialization in the market. It requires a thoughtful understanding of the correlation between their specific structure and property. Here, the structural and optical properties of an important HDP-based (NH4)2SeBr6 are investigated under high pressure. A dramatic piezochromism is found with the increase in pressure. Optical absorption spectra reveal the pressure-induced red-shift in bandgap with two distinct anomalies at 6.57 and 11.18 GPa, and the energy tunability reaches 360 meV within 20.02 GPa. Combined with structural characterizations, Raman and infrared spectra, and theoretical calculations using density functional theory, results reveal that, the first anomaly is caused by the formation of a Br-Br bond among the 2- octahedra, and the latter is attributed to a cubic-to-tetragonal phase transition. These results provide a clear correlation between the chemical bonding and optical properties of (NH4)2SeBr6. It is believed that the proposed strategy paves the way to optimize the optoelectronic properties of HDPs and further stimulate the development of next-generation clear energy based on HDPs solar cells. © 2020 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.It was recently recognized that cancer therapeutic efficacy may be greatly compromised by an intrinsic protective mechanism called autophagy, by which cancer cells survive in harsh conditions such as starvation. Here, a synergetic strategy is described for cancer treatment by suppressing such a protective mechanism for augmenting tumor-starvation therapy. The synergetic therapy is achieved by restraining glucose metabolism using an antiglycolytic agent to predispose cancer cells to severe energy deprivation; concurrently the downstream autophagic flux and compensatory energy supplies are blocked by the autophagy inhibitor black phosphorus nanosheet. Cancer cells fail to extract their own nutrient to feed themselves, finally succumbing to therapeutic interventions and starving to death. Both in vitro and in vivo results evidence the cooperative effect between the autophagy inhibitor and antiglycolytic agent, which leads to remarkable synergetic antineoplastic outcome. It is expected that such a combinational approach by concurrently blocking exogenous and endogenous nutrition supplies will be beneficial to the design of effective tumor-specific cancer therapies in the future. © 2020 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.Cu2O nanoparticles (NPs) enclosed with different crystal facets, namely, c-Cu2O NPs with 100 facets, o-Cu2O NPs with 111 facets, and t-Cu2O NPs with both 111 and 100 facets, are prepared and their electrocatalytic properties for the reduction of CO2 to C2H4 are evaluated. It is shown that the selectivity and activity of the C2H4 production depend strongly on the crystal facets exposed in Cu2O NPs. The selectivities for the C2H4 production increases in the order, c-Cu2O less then o-Cu2O less then t-Cu2O, (with FEC2H4 = 38%, 45%, and 59%, respectively). This study suggests that Cu2O NPs are more likely responsible for the selectivity and activity for the C2H4 production than the metallic Cu NPs produced on the surface of Cu2O NPs. This work provides a new route for enhancing the selectivity of the electrocatalytic CO2 reduction by crystal facet engineering. © 2020 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.MnO2 is one of the most studied cathodes for aqueous neutral zinc-ion batteries. However, the diverse reported crystal structures of MnO2 compared to δ-MnO2 inevitably suffer a structural phase transition from tunneled to layered Zn-buserite during the initial cycles, which is not as kinetically direct as the conventional intercalation electrochemistry in layered materials and thus poses great challenges to the performance and multifunctionality of devices. Here, a binder-free δ-MnO2 cathode is designed and a favorable “layered to layered” Zn2+ storage mechanism is revealed systematically using such a “noninterferencing” electrode platform in combination with ab initio calculation. A flexible quasi-solid-state Zn-Mn battery with an electrodeposited flexible Zn anode is further assembled, exhibiting high energy density (35.11 mWh cm-3; 432.05 Wh kg-1), high power density (676.92 mW cm-3; 8.33 kW kg-1), extremely low self-discharge rate, and ultralong stability up to 10 000 cycles. Even with a relatively high δ-MnO2 mass loading of 5 mg cm-2, significant energy and power densities are still achieved. The device also works well over a broad temperature range (0-40 °C) and can efficiently power different types of small electronics. This work provides an opportunity to develop high-performance multivalent-ion batteries via the design of a kinetically favorable host structure. © 2020 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.Fiber microactuators are interesting in wide variety of emerging fields, including artificial muscles, biosensors, and wearable devices. In the present study, a robust, fast-responsive, and humidity-induced silk fiber microactuator is developed by integrating force-reeling and yarn-spinning techniques. The shape gradient, together with hierarchical rough surface, allows these silk fiber microactuators to respond rapidly to humidity. The silk fiber microactuator can reach maximum rotation speed of 6179.3° s-1 in 4.8 s. Vismodegib in vivo Such a response speed (1030 rotations per minute) is comparable with the most advanced microactuators. Moreover, this microactuator generates 2.1 W kg-1 of average actuation power, which is twice higher than fiber actuators constructed by cocoon silks. The actuating powers of silk fiber microactuators can be precisely programmed by controlling the number of fibers used. Lastly, theory predicts the observed performance merits of silk fiber microactuators toward inspiring the rational design of water-induced microactuators.